A new scientific paper titled “Harnessing Next-Generation 3D Cancer Models to Elucidate Tumor-Microbiome Crosstalk” has been published in the journal Advanced Healthcare Materials.
The review explores how advanced 3D cancer models — including organoids, spheroids, organ-on-chip platforms and 3D bioprinted systems — are opening new perspectives in the study of tumor–microbiome interactions. The paper highlights the role of the microbiome in influencing tumor progression, immune responses and treatment outcomes across several cancer types, while also discussing the technological challenges and opportunities associated with these emerging models.
The publication was produced in the framework of the TIMNano project, contributing to the project’s efforts to advance interdisciplinary research at the intersection of nanotechnology, oncology and biomedical engineering. The paper further underlines the importance of innovative in vitro models to support more predictive cancer research and the development of future precision medicine approaches.
Read the paper here.
